Описание
Immunogen: KLH conjugated synthetic peptide derived from human CLASP2
Storage: Long term: -20°C; Short term: +4°C
Tested Reacted Species: Human, Mouse, Rat, Dog, Pig, Horse,
Isotype: IgG
Mol wt: predicted molecular weight: 141kDa
Recommended Application: WB,ELISA,IP,IHC-P,IHC-F,IF Size: 200ug（1mg/ml）
Background Information：
CLASP2 is a microtubule plus end tracking protein that promotes the stabilization of dynamic microtubules and is
required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the
cell. CLASP2 may act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by
attaching their plus ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing
activity is regulated at least in part by phosphatidylinositol 3 kinase signaling. CLASP2 also performs a similar
stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic
spindle
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